BNIP3 ELISA Kit for Human(Homo sapiens) | EIAab.comBNIP3 ELISA Kit for Human(Homo sapiens)

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BNIP3 (Gene name),

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (Protein name ), BNIP3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

BNIP3(NIP3);

Protein name:

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Binds to BCL2. Interacts with BNIP3L and ACAA2. Also can interact with adenovirus E1B 19 kDa protein or Epstein-Barr virus BHRF1.

Function:

Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.

Subcellular Location:

Mitochondrion Mitochondrion membrane Single-pass membrane protein Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria.

Protein Attributes:

Sequence length:

194

Sequence:

50:

100:

150:

194:

MKKGGIFSAE | FLKVFLPSLL | LSHLLAIGLG | IYIGRRLTTS | TSTF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000357625

UniGene:

Hs.144873

KEGG:

hsa:664

Pfam:

PF06553

String:

Q12983

MIM:

603293

SMR:

Q12983

Uniprot:

Q12983

FOR

ELISA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Cat.:

E15232m

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Manual:

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Packing:

96T

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ELISA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Cat.:

E15232h

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Packing:

96T

ELISA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Cat.:

E15232b

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Packing:

96T

CLIA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Cat.:

U15232m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Cat.:

U15232b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Cat.:

U15232h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Cat.:

P15232Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Cat.:

P15232Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Protein for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
2.

"S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3."
Ghavami S. , Eshragi M. , Ande S.R. , Chazin W.J. , Klonisch T. , Halayko A.J. , McNeill K.D. , Hashemi M. , Kerkhoff C. , Los M.
Cell Res.20:314-331(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
3.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-86;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
4.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
5.

"BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria."
Nakamura Y. , Kitamura N. , Shinogi D. , Yoshida M. , Goda O. , Murai R. , Kamino H. , Arakawa H.
PLoS ONE7:E30767-E30767(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SPATA18;SUBCELLULAR LOCATION
6.

"Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins."
Boyd J.M. , Malstrom S. , Subramanian T. , Venkatesh L.K. , Schaeper U. , Elangovan B. , D'Sa-Eipper C. , Chinnadurai G.
Cell79:341-351(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH BCL2
tissue: B-cell.
7.

"The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis."
Chen G. , Ray R. , Dubik D. , Shi L. , Cizeau J. , Bleackley R.C. , Saxena S. , Gietz R.D. , Greenberg A.H.
J. Exp. Med.186:1975-1983(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: B-cell.
8.

NIEHS SNPs program
Submitted (2005-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
9.

"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
11.

"A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region."
Ohi N. , Tokunaga A. , Tsunoda H. , Nakano K. , Haraguchi K. , Oda K. , Motoyama N. , Nakajima T.
Cell Death Differ.6:314-325(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BNIP3L
12.

"Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines."
Cao W. , Liu N. , Tang S. , Bao L. , Shen L. , Yuan H. , Zhao X. , Lu H.
Biochim. Biophys. Acta1780:873-880(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH ACAA2

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